Dynamics of ribonuclease A and ribonuclease S: Computational and experimental studies
نویسندگان
چکیده
منابع مشابه
Studies on Ribonuclease S
Specific regions of the polypeptide sequence of pancreatic ribonuclease have been altered by chemical modification and by limited proteolytic digestion in attempts to implicate specific covalent portions of the molecule in the structure and stabilization of the active center. Digestion of the native molecule with trypsin at elevated temperatures has been shown to remove portions of the chain wi...
متن کاملStudies on Ribonuclease S. I. Limited Carboxypeptidase Degradation of Ribonuclease S-protein and Ribonuclease S-peptide: Effects of Changes in Primary Structure on Enzymic Activity.
Specific regions of the polypeptide sequence of pancreatic ribonuclease have been altered by chemical modification and by limited proteolytic digestion in attempts to implicate specific covalent portions of the molecule in the structure and stabilization of the active center. Digestion of the native molecule with trypsin at elevated temperatures has been shown to remove portions of the chain wi...
متن کاملOptical activity of cystine-containing proteins. II. Circular dichroism spectra of pancreatic ribonuclease A, ribonuclease S, and ribonuclease S-protein.
The circular dichroism spectra of pancreatic ribonuclease A, RNase S, and RNase S-protein have been measured in the wave length interval 198 to 300 mp under various conditions. The circular dichroism spectra of RNase A and S are very similar, possibly identical, over this entire wave length interval at neutral pH. That of RNase S-protein is substantially different. It is shown that the portion ...
متن کاملsimulation and experimental studies for prediction mineral scale formation in oil field during mixing of injection and formation water
abstract: mineral scaling in oil and gas production equipment is one of the most important problem that occurs while water injection and it has been recognized to be a major operational problem. the incompatibility between injected and formation waters may result in inorganic scale precipitation in the equipment and reservoir and then reduction of oil production rate and water injection rate. ...
Crystalline semisynthetic ribonuclease-S'.
Crystals of solid phase-derived semisynthetic ribonuclease-S' were prepared and compared with those for native ribonuclease-S' and -S. The semisynthetic species used was the noncovalent complex of synthetic fragment-(1-20), corresponding to residues 1 through 20 of bovine pancreatic ribonuclease-A (ribonucleate 3'-pyrimidino-oligonucleotidohydrolase, EC 3.1.4.22), and native ribonuclease-S-(21-...
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ژورنال
عنوان ژورنال: Protein Science
سال: 1996
ISSN: 0961-8368,1469-896X
DOI: 10.1002/pro.5560051017